AROUND LAB NEWS / EN » Chemistry Education http://www.aroundlabnews.com/en Tue, 27 Feb 2018 15:10:59 +0000 it-IT hourly 1 http://wordpress.org/?v=3.5.1 MOLECULE OF THE YEAR http://www.aroundlabnews.com/en/molecule-of-the-year/ http://www.aroundlabnews.com/en/molecule-of-the-year/#comments Tue, 07 Jun 2016 07:58:35 +0000 AROUND LAB NEWS / EN http://www.aroundlabnews.com/en/?p=5529 Sleeping Beauty” named Molecule of the year.

Tracy Vence

The transposon was chosen by the International Society for Molecular and Cell Biology and Biotechnology Protocols and Research for enabling stable gene transfer in vertebrates.

The International Society for Molecular and Cell Biology and Biotechnology Protocols and Research (ISMCBBPR) has named “Sleeping Beauty” (SB)/transposase SB100X as Molecule of the Year 2009 as part of its annual competition. According to the ISMCBBPR, Sleeping Beauty was chosen by voters because researchers have demonstrated its ability to enable robust, stable gene transfer in vertebrates. The synthetic transposon received the top honor over 14 other nominees, including runners-up sarcosine, human occludin protein, and mina. Each nominated molecule was featured during the past year in a peer-reviewed research paper that described the protocol used to decipher its role.

image001

Diagram outlining the life cycle of the “Sleeping Beauty” (SB) transposon. Source: WikiMedia Commons.

SB, when combined with a transposase, mediates the stable integration and long-term expression of a gene of interest. A team of researchers—from the Max Delbrück Center for Molecular Medicine in Berlin-Buch and the Catholic University of Leuven, Belgium—demonstrated that SB/SB100X efficiently mediated gene transfer in human CD34+ cells enriched in hematopoietic stem or progenitor cells. The novel transposase was described in the June 2009 Nature Genetics paper, “Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates.”According to the researchers, SB/SB100X has the potential to improve current transfection methods used in functional genomics and gene therapy.

“The synthetic transposon ‘Sleeping Beauty’ and the corresponding hyperactive transposase SB100X bring about a revolutionary technology platform for genetic engineering in vertebrates,” the ISMCBBPR web site reads. “This molecule holds great promise for gene therapy as it addresses a major hurdle in gene therapeutic applications, especially those revealed by viral transduction approaches [and] site-specific integration.”

Seven presidents of international molecular and cellular biology and biotechnology organizations judged the competition. The judges considered each molecule’s potential for future contribution to biology or medical research.

Past awardees include anti-SAG 421-433 catalytic IgA, protein 4E1 , and the ligand Imidazoleacetic acid-ribotide.

Keywords:  “Sleeping Beauty” transposon transposase gene expression gene therapy

]]> http://www.aroundlabnews.com/en/molecule-of-the-year/feed/ 0 Where can you find information about the “microarray” technique? http://www.aroundlabnews.com/en/where-can-you-find-information-about-the-microarray-technique/ http://www.aroundlabnews.com/en/where-can-you-find-information-about-the-microarray-technique/#comments Tue, 02 Feb 2016 16:31:06 +0000 AROUND LAB NEWS / EN http://www.aroundlabnews.com/en/?p=5384 www.microarrayworld.com 

Every technical aspect relevant to “microarray” technology is described in details.

]]> http://www.aroundlabnews.com/en/where-can-you-find-information-about-the-microarray-technique/feed/ 0 Where can you find information about chemistry and bio-chemistry? http://www.aroundlabnews.com/en/where-can-you-find-information-about-chemistry-and-bio-chemistry/ http://www.aroundlabnews.com/en/where-can-you-find-information-about-chemistry-and-bio-chemistry/#comments Tue, 02 Feb 2016 16:30:26 +0000 AROUND LAB NEWS / EN http://www.aroundlabnews.com/en/?p=5382 www.elmhurst.edu/~chm/vchembook 

Virtual Chem Book online offers spanning scientific disciplines from general chemistry to biochemistry.

 

]]> http://www.aroundlabnews.com/en/where-can-you-find-information-about-chemistry-and-bio-chemistry/feed/ 0 Where can you find information about chemical compounds? http://www.aroundlabnews.com/en/where-can-you-find-information-about-chemical-compounds/ http://www.aroundlabnews.com/en/where-can-you-find-information-about-chemical-compounds/#comments Tue, 02 Feb 2016 16:29:21 +0000 AROUND LAB NEWS / EN http://www.aroundlabnews.com/en/?p=5379 http://chembank.broadinstitute.org/welcome.htm 

Information available online about 800.000 commercially available chemical compounds. At the “Chembank” users can search through chemical data by several means, including structure, substructure,  similarity to a structure by description, function, assay, name and even a particular person or vendor.

 

]]> http://www.aroundlabnews.com/en/where-can-you-find-information-about-chemical-compounds/feed/ 0 The analytical tests present inside the 6.6. Supplement of European Pharmacopeia http://www.aroundlabnews.com/en/the-analytical-tests-present-inside-the-6-6-supplement-of-european-pharmacopeia/ http://www.aroundlabnews.com/en/the-analytical-tests-present-inside-the-6-6-supplement-of-european-pharmacopeia/#comments Mon, 12 Oct 2015 07:24:51 +0000 AROUND LAB NEWS / EN http://www.aroundlabnews.com/en/?p=5143 Answer:

2.2.31 Electrophoresis
2.2.42 Density of solids
2.2.47 Capillary electrophoresis
2.2.54 Isoelectric focusing
2.2.55 Peptide focusing
2.2.56 Amino acid analysis
2.4.29 Composition of fatty oils rich in omega-3 acids
2.6.14 Bacterial endotoxins
2.6.17 Test or anti-complimentary activity of immunoglobulin
2.9.3. Dissolution test for solid dosage forms
2.9.7. Friability of uncoated tablets
2.9.37 Optical microscopy
2.3.2. Identification of fatty oils by thin-layer chromatography
2.4.22 Composition of fatty acids by gas chromatography
5.1.3. Efficacy of anti-microbial preservation
]]> http://www.aroundlabnews.com/en/the-analytical-tests-present-inside-the-6-6-supplement-of-european-pharmacopeia/feed/ 0 Existence of Element 117 Confirmed http://www.aroundlabnews.com/en/existence-of-element-117-confirmed-2/ http://www.aroundlabnews.com/en/existence-of-element-117-confirmed-2/#comments Sat, 07 Jun 2014 08:05:12 +0000 AROUND LAB NEWS / EN http://www.aroundlabnews.com/en/?p=4617 Element 117, first discovered by Lawrence Livermore researchers and Russian collaborators, has been reproduced by an international consortium. The IUPAC must accept the confirmation before the element is named. Image: Lawrence LivermoreElement 117, first discovered by Lawrence Livermore scientists and international collaborators in 2010, is one step closer to being named.

The existence of element 117 and its decay chain to elements 115 and 113 have been confirmed by a second international team led by scientists at GSI Helmholtz Centre for Heavy Ion Research, an accelerator laboratory. The research will appear in an upcoming issue of the journal, Physical Review Letters.

The next step is for the International Union of Pure and Applied Chemistry (IUPAC) to accept the confirmation. The IUPAC will review the new findings and the original research and decide whether further experiments are needed before acknowledging the element’s discovery. After acceptance, IUPAC would determine which institution may propose names.

In the German experiments, scientists bombarded a berkelium target with calcium ions until they collided and formed element 117. Element 117 then decayed into elements 115 and 113. Livermore researchers Narek Gharibyan and Dawn Shaughnessy and former postdoc Evgeny Tereshatov participated in the German experiment.

Lawrence Livermore teamed with the Joint Institute for Nuclear Research in Russia (JINR) in 2004 to discover elements 113 and 115. The LLNL/JINR team then jointly worked with researchers from the Research Institute for Advanced Reactors, Oak Ridge National Laboratory, Vanderbilt Univ. and the Univ. of Nevada, Las Vegas, to discover element 117 in 2010.

Elements beyond atomic number 104 are referred to as super-heavy elements. The most long-lived ones are expected to be situated on a so-called “island of stability,” where nuclei with extremely long half-lives should be found.

Although super-heavy elements have not been found in nature, they can be produced by accelerating beams of nuclei and shooting them at the heaviest possible target nuclei. Fusion of two nuclei — a very rare event — occasionally produces a super-heavy element. They generally only exist for a short time

Font:  Laboratory Equipment

]]> http://www.aroundlabnews.com/en/existence-of-element-117-confirmed-2/feed/ 0 Existence of Element 117 Confirmed http://www.aroundlabnews.com/en/existence-of-element-117-confirmed/ http://www.aroundlabnews.com/en/existence-of-element-117-confirmed/#comments Fri, 23 May 2014 10:29:37 +0000 AROUND LAB NEWS / EN http://www.aroundlabnews.com/en/?p=4576 Element 117, first discovered by Lawrence Livermore researchers and Russian collaborators, has been reproduced by an international consortium. The IUPAC must accept the confirmation before the element is named. Image: Lawrence LivermoreElement 117, first discovered by Lawrence Livermore scientists and international collaborators in 2010, is one step closer to being named.

The existence of element 117 and its decay chain to elements 115 and 113 have been confirmed by a second international team led by scientists at GSI Helmholtz Centre for Heavy Ion Research, an accelerator laboratory. The research will appear in an upcoming issue of the journal, Physical Review Letters.

The next step is for the International Union of Pure and Applied Chemistry (IUPAC) to accept the confirmation. The IUPAC will review the new findings and the original research and decide whether further experiments are needed before acknowledging the element’s discovery. After acceptance, IUPAC would determine which institution may propose names.

In the German experiments, scientists bombarded a berkelium target with calcium ions until they collided and formed element 117. Element 117 then decayed into elements 115 and 113. Livermore researchers Narek Gharibyan and Dawn Shaughnessy and former postdoc Evgeny Tereshatov participated in the German experiment.

Lawrence Livermore teamed with the Joint Institute for Nuclear Research in Russia (JINR) in 2004 to discover elements 113 and 115. The LLNL/JINR team then jointly worked with researchers from the Research Institute for Advanced Reactors, Oak Ridge National Laboratory, Vanderbilt Univ. and the Univ. of Nevada, Las Vegas, to discover element 117 in 2010.

Elements beyond atomic number 104 are referred to as super-heavy elements. The most long-lived ones are expected to be situated on a so-called “island of stability,” where nuclei with extremely long half-lives should be found.

Although super-heavy elements have not been found in nature, they can be produced by accelerating beams of nuclei and shooting them at the heaviest possible target nuclei. Fusion of two nuclei — a very rare event — occasionally produces a super-heavy element. They generally only exist for a short time

Font:  Laboratory Equipment

Read more: Link >>>

 

]]> http://www.aroundlabnews.com/en/existence-of-element-117-confirmed/feed/ 0 Spettroscopia: International Council for NIR (Near Infrared Spectroscopy) http://www.aroundlabnews.com/en/spettroscopia-international-council-for-nir-near-infrared-spectroscopy/ http://www.aroundlabnews.com/en/spettroscopia-international-council-for-nir-near-infrared-spectroscopy/#comments Fri, 10 Jan 2014 08:19:35 +0000 AROUND LAB NEWS / EN http://www.aroundlabnews.com/en/?p=4276 NIR News  in Tablet Edition is the official publication of the ICNIS. It informs and educated and keeps the NIR community in touch with all the latest news, events and developments around the world. Its articles give an excellent overview of current research and cover a wide range of fields and its technical columns provide useful hints.

www.impublications.com/tablet

 

]]> http://www.aroundlabnews.com/en/spettroscopia-international-council-for-nir-near-infrared-spectroscopy/feed/ 0 The correct ergonomy with micropipettes http://www.aroundlabnews.com/en/the-correct-ergonomy-with-micropipettes/ http://www.aroundlabnews.com/en/the-correct-ergonomy-with-micropipettes/#comments Fri, 20 Sep 2013 12:45:46 +0000 AROUND LAB NEWS / EN http://www.aroundlabnews.com/en/?p=4185

 

]]> http://www.aroundlabnews.com/en/the-correct-ergonomy-with-micropipettes/feed/ 0 Symbols of chemistry elements http://www.aroundlabnews.com/en/symbols-of-chemistry-elements/ http://www.aroundlabnews.com/en/symbols-of-chemistry-elements/#comments Tue, 17 Sep 2013 08:47:00 +0000 AROUND LAB NEWS / EN http://www.aroundlabnews.com/en/?p=4088

ELEMENT 

SYMBOL

 

ELEMENT

SYMBOL

Actinium 

 Ac

 

 Mercury

Hg 

 Aluminium

 Al

 

 Molybdenum

 Mo

 Americium

 Am

 

 Neodymium

 Nd

 Antimony

 Sb

 

 Neon

 Ne

 Argon

 Ar

 

 Neptunium

 Np

 Arsenic

 As

 

 Nickel

 Ni

 Astatine

 At

 

 Niobium

 Nb

 Barium

 Ba

 

 Nitrogen

 N

 Berkelium

 Bk

 

 Nobelium

 No

 Beryllium

 Be

 

 Osmium

 Os

 Bismuth

 Bi

 

 Oxygen

 O

 Boron

 B

 

 Palladium

 Pd

Bromine

 Br

 

 Phosphorus

 P

Cadmium

 Cd

 

 Platinum

 Pt

 Calcium

 Ca

 

 Plutonium

 Pu

Californium

 Cf

 

Polonium

 Po

Carbon

 C

 

 Potassium

 K

Cerium

 Ce

 

 Praseodymium

 Pr

Cesium

 Cs

 

 Promethium

 Pm

Chlorine

 Cl

 

 Protactinium

 Pa

Chromium

 Cr

 

 Radium

 Ra

 Cobalt

 Co

 

 Radon

 Rn

Copper

 Cu

 

 Rhenium

 Re

Curium

 Cm

 

 Rhodium

 Rh

Dysprosium

 Dy

 

 Rubidium

 Rh

Einsteinium

 Es

 

 Ruthenium

 Ru

Erbium

 Er

 

 Samarium

 Sm

Europium

 Eu

 

 Scandium

 Sc

Fermium

 Fm

 

 Selenium

 Se

Fluorine

 F

 

 Silicon

 Si

 Francium

 Fr

 

 Silver

 Ag

 Gadolinium

 Gd

 

 Sodium

 Na

 Gallium

 Ga

 

 Strontium

Sr

Germanium

 Ge

 

 Sulftir

 S

Gold

 Au

 

 Tantalum

 Ta

Hafnium

 Hf

 

 Technetium

 Tc

Helium

 He

 

 Tellerium

 Te

Holmium

 Ho

 

 Terbium

 Tb

Hydrogen

 H

 

 Thallium

 Ti

 Indium

 In

 

 Thorium

 Th

Iodine

 I

 

 Thulium

 Tm

Iridium

 Ir

 

 Tin

 Sn

Iron

 Fe

 

 Titanium

 Ti

Krypton

 Kr

 

 Tungsten

 W

 Lanthanum

 La

 

 Uranium

 U

 Lawrencium

 Lr

 

 Vanadium

 V

 Lead

 Pb

 

 Xenon

 Xe

 Lithium

 Li

 

 Ytterbium

 Yb

Lutetium

 Lu

 

 Yttrium

 Y

Magnesium

 Mg

 

 Zinc

 Zn

Manganese

 Mn

 

 Zirconium

 Zr

Mendelevium

 Md

 

   

Font: Nature

 

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